Nano Silver Fluoride – A potential non-invasive solution to treat dental caries

Abstract :

Dental decay is one of the paediatric disorders requiring early intervention and can lead to tooth loss if not treated. Antimicrobial medicines work by altering the nature of pathogenic microorganisms in dental biofilms to reduce cariogenic activity. When fluoride is mixed with silver, which has an antibacterial effect, its antimicrobial efficiency is boosted. Silver diamine Fluoride has been shown to aid in the prevention of tooth decay, with the only drawback being an unsightly black discoloration. Silver nanoparticles with an appropriate surface range and a huge proportion of surface atoms have attracted attention due to their distinguishing characteristics. Although Silver diamine Fluoride has altered dentin collagen shape and Nano silver fluoride has normal collagen fibrils, both show intrafibrillar remineralization. Nano silver fluoride is a topical agent which can be safely, and cost-effectively applied to children for treating dental caries.

Keywords:
  • Caries,
  • Children
  • Silver diamine Fluoride,
  • Nano silver fluoride,
  • antimicrobial
Reference

[1] Cheng L, Zhang L, Yue L, Ling J, Fan M, Yang D, et al. Expert consensus on dental caries management. International Journal of Oral Science. 2022;14(1):17.

[2] Shimpo Y, Nomura Y, Sekiya T, Arai C, Okada A, Sogabe K, et al. Effects of the Dental Caries Preventive Procedure on the White Spot Lesions during Orthodontic Treatment—An Open Label Randomized Controlled Trial. Journal of Clinical Medicine. 2022;11(3):854.

[3] Ruff RR, Whittemore R, Grochecki M, Bateson J, Barry Godín TJ. Silver diamine fluoride and oral health-related quality of life: A review and network meta-analysis. PLoS One. 2022;17(2):e0261627.

[4] Wajahat M, Abbas B, Tariq K, Imran E, Aslam S, Khurshid Z. Parental perception of silver diamine fluoride for the management of dental caries. Journal of Taibah University Medical Sciences. 2022.

[5] Contreras V, Toro MJ, Elías-Boneta AR, Encarnación-Burgos A. Effectiveness of silver diamine fluoride in caries prevention and arrest: a systematic literature review. General dentistry. 2017;65(3):22-9.

[6] Kristine R. Crews. Pharmacogenomics and individualized medicine: Translating science into practice. Clin Pharmacol Ther 2012;92:467–75.

[7] Evans WE, McLeod HL. Pharmacogenomics - drug disposition, drug targets, and side effects. New Engl J Med 2003;348:538-49.

[8] A. Dong, J. Huang, S. Lan, T. Wang, L. Xiao, W. Wang, et al., Synthesis of N-halamine-functionalized silica-polymer core-shell nanoparticles and their enhanced antibacterial activity, Nanotechnology 22 (2011) 19.

[9] Suzuki K. A review of computer-aided diagnosis in thoracic and colonic imaging. Quant Imaging Med Surg 2012;2:163–76

[10]Naranjo J, Poniachik J, Cisco D, et al. Oral Ulcers Produced by Mycophenolate Mofetil in Two Liver Transplant Patients. Transplant Proc. 2007;39(3):612-614. doi:10.1016/j.transproceed.2006.12.028

[11]Evans WE, McLeod HL. Pharmacogenomics - drug disposition, drug targets, and side effects. New Engl J Med 2003;348:538-49.

[12]Hung M, Voss MW, Rosales MN, et al. Application of machine learning for diagnostic prediction of root caries. Gerodontology 2019;36:395e404

[13]Garrigue V.; Canet, S.; Dereure, O.; Panabieres, O.; Augias, D.; Chong, G.; Mourad G. ORAL ULCERATIONS IN A RENAL TRANSPLANT RECIPIENT: A

[14] Stiphout MAE Van, Marinus J, Hilten JJ Van, Lobbezoo F, Baat C De. Oral Health of Parkinson ’ s Disease Patients : A Case-Control Study. 2018;2018.

[15].Garrigue V.; Canet, S.; Dereure, O.; Panabieres, O.; Augias, D.; Chong, G.; Mourad G. ORAL ULCERATIONS IN A RENAL TRANSPLANT RECIPIENT: A

[16]A. Dong, J. Huang, S. Lan, T. Wang, L. Xiao, W. Wang, et al., Synthesis of N-halamine-functionalized silica-polymer core-shell nanoparticles and their enhanced antibacterial activity, Nanotechnology 22 (2011) 19.

[17]Thanathornwong B. Bayesian-based decision support system for assessing the needs for orthodontic treatment. Healthc Inform Res 2018;24:22e8

[18] Yu HJ, Cho SR, Kim MJ, Kim WH, Kim JW, Choi J. Automated skeletal classification with lateral cephalometry based on artificial intelligence. J Dent Res 2020;99:249e56.

[19]S. Nugen, M. Hiorth, M. Rykke, G. Smistad, The potential of liposomes as dental drug delivery systems, Eur. J. Pharm. Biopharm. 77 (2011) 75 83.

[20]Silva AVC, Teixeira JdA, Melo PCd, Lima MGdS, Mota CCBdO, Lins ECCC, et al. Remineralizing potential of nano-silver-fluoride for tooth enamel: an optical coherence tomography analysis. Pesquisa Brasileira em Odontopediatria e Clínica Integrada. 2019;19.

[21] Nozari A, Ajami S, Rafiei A, Niazi E. Impact of nano hydroxyapatite, nano silver fluoride and sodium fluoride varnish on primary teeth enamel remineralization: an in vitro study. Journal of clinical and diagnostic research: JCDR. 2017;11(9):ZC97.

[22] Zameer M, Birajdar SB, Basheer SN, Peeran SW, Peeran SA, Reddy A. Nanosilver fluoride as a caries arresting agent: A narrative. Contemp Pediatr. 2021;2(1):1-13.

© The Author(s), under exclusive license to Technoarete Publishers 2022
  • ISBN - 978-93-92104-02-2
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  • Total No. of. Pages - 150
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10.36647/ETOHSD/2022.01.B1.Ch012