Term personalized medicine refers a medical model in which healthcare, medical decisions are customized and/or products to be used are tailored based on the need of the individual patient. In personalized medicine physicians and dentist recognize the variation between each patients to provide custom made concern in shape of health among the individual1 . As periodontal disease is a complex interaction of genetic factors, biological factors, behavioral factors, environmental factors and other factors, susceptibility and expression of disease differs from individuals2 . The term “Personalized medicine”, is not a new approach but it is an extension form of ethinic approaches in understanding and treating disease with higher precision3 .

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[11]Evans WE, McLeod HL. Pharmacogenomics - drug disposition, drug targets, and side effects. New Engl J Med 2003;348:538-49.

[12]Wang Y, Zhou J, Fu S, Wang C, Zhou B. A Study of Association Between Oral Lichen Planus and Immune Balance of Th1/Th2 Cells. Inflammation. 2015;38(5):1874-1879.

[13]Garrigue V.; Canet, S.; Dereure, O.; Panabieres, O.; Augias, D.; Chong, G.; Mourad G. ORAL ULCERATIONS IN A RENAL TRANSPLANT RECIPIENT: A

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[15].Garrigue V.; Canet, S.; Dereure, O.; Panabieres, O.; Augias, D.; Chong, G.; Mourad G. ORAL ULCERATIONS IN A RENAL TRANSPLANT RECIPIENT: A

[16]Zhang, X., Liang, Y., Li, W., Liu, C., Gu, D., Sun, W., & Miao, L. (2020). Development and evaluation of deep learning for screening dental caries from oral photographs. Oral diseases, 10.1111/odi.13735. Advance online publication.

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[18] Giannobile WV, Braun TM, Caplis AK, Doucette-Stamm L, Duff GW, Kornman KS. Patient stratification for preventive care in dentistry. J Dent Res 2013;92:694-701

[19]Schwendicke F, Rossi JG, Göstemeyer G, et al. Cost-effectiveness of Artificial Intelligence for Proximal Caries Detection. J Dent Res. 2021;100(4):369-376

[20]Engebretson SP, Grbic JT, Singer R, Lamster IB. GCF IL1beta profiles in periodontal disease. J Clin Periodontol 2002;29:48-53